A Central America cruise can take you eastbound or westbound across the Panama Canal. Explore the Pacific ports of Panama City, Puntarenas, and even Puerto Quetzal in Guatemala. You can visit Colón or explore other Caribbean destinations on the Caribbean side of the Panama Canal. Central America is known for its lush jungles, remote beaches, and eco-tourism opportunities. When you book a Central America cruise with Big Time Holidays, you get all the amenities of a multi-destination vacation to Central America with all the fun of traveling by sea.